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WEIGHT LOSS IN BARIATRIC SURGERY | Healthy Cocoberry

WEIGHT LOSS IN BARIATRIC SURGERY

Home / General / WEIGHT LOSS IN BARIATRIC SURGERY

WEIGHT LOSS IN BARIATRIC SURGERY

There is clear evidence that gastric bypass surgery causes weight loss by many mechanisms such as causing malabsorption of nutrients. However the total weight loss cannot be explained by this alone

There are millions of bacteria in our intestines weighing 3-5 lbs. They are very active and this is called the microbiotome, Recent studies have implicated weight gain with the types of bacteria in our intestines

There is new evidence that gut bacteria is a major cause of weight in obese individuals. A recent study has shown that changing these bacteria is a cause of weight loss in patients having gastric surgery

A clear correlation exists of microbiome composition and gene function with an improvement in metabolic and inflammatory parameters. This will allow to develop new diagnostic and therapeutic strategies based on metagenomic sequencing of the human gut microbiome.
Based on this we may be very soon able to help to understand the inability to lose weight as well as many other diseases which we did not understand before

reference

The Pharmacogenomics Journal (2013) 13, 514–522; doi:10.1038/tpj.2012.43; published online 2 October 2012

Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters

J Graessler1,6, Y Qin2,6, H Zhong2,6, J Zhang2,6, J Licinio3, M-L Wong3, A Xu4, T Chavakis1, A B Bornstein1, M Ehrhart-Bornstein1, V Lamounier-Zepter1, T Lohmann5, T Wolf5 and S R Bornstein1,6

1Department of Internal Medicine III, Carl Gustav Carus Medical School, Technical University Dresden, Dresden, Germany
2Research and Cooperation Division, BGI-Shenzhen, Shenzhen, China
3Department of Translational Medicine, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia
4Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
5Department of Internal Medicine, Dresden Interdisciplinary Adiposity Center, Community Hospital Dresden-Neustadt, Dresden, Germany
Correspondence: Professor SR Bornstein, Department of Internal Medicine III, Carl Gustav Carus Medical School, Technical University Dresden, Fetscherstrasse 74, Dresden D-01307, Germany. E-mail: Stefan.Bornstein@uniklinikum-dresden.de

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Received 6 August 2012; Revised 15 August 2012; Accepted 20 August 2012
Advance online publication 2 October 2012