Preoperative vitamin D blood levels were significantly and inversely associated with risk for hospital-acquired infections after gastric bypass surgery, researchers found.
Among obese patients with 25-hydroxyvitamin D levels lower than 30 ng/mL, there was a three-fold risk for a hospital-acquired infection after surgery versus patients whose vitamin D levels were 30 ng/mL or higher (adjusted odds ratio 3.05, 95% CI 1.34-6.94, according toSadeq Quraishi, MD, of Massachusetts General Hospital (MGH) in Boston, and colleagues. They wrote this online in JAMA Surgery.
Low serum vitamin D has been tied to risk of hip osteoarthritis in older men andincreased odds of heart failure versus those with normal serum levels, while elevated concentrations have been associated with decreased risk for ear infection in children.
The authors noted that vitamin D insufficiency “may be as high as 70% to 80% in bariatric surgery patients,” while rates of surgical site infections are as high as 10% among Roux-en-Y gastric bypass surgery patients in laparoscopic procedures and as high as 25% among open abdominal surgery.
They studied the association between hospital-acquired infections and vitamin D serum concentration in a population of 770 Roux-en-Y gastric bypass surgery patients treated at MGH.
Patient data was gathered through the hospital’s research patient data registry.
Vitamin D concentrations “are routinely measured in individuals scheduled to undergo Roux-en-Y gastric bypass surgery” at the site during a preoperative nutrition assessment, the authors stated.